Abstract

In this study, we present a numerical simulation of the impact of relapse on Hepatitis B virus transmission dynamics. The sensitivity analysis result establishes that relapse rate increases the value of the effective reproduction number when it is increased. Similarly, the result of the numerical simulation reveals that relapse increases the number of infected persons and thus the spread of the Hepatitis B Virus. Also, it delays the quick response to the treatment regimen which consequently slows down the potential of recovery from the infection. However, new drugs with low resistance should be provided, that will help to minimize the risk of relapse / re-emergence of the infection due to drug resistance.